Mobile gait analysis for hereditary spastic paraplegia patients

Hereditary spastic paraplegias (HSPs) are a group of genetic disorders whose predominant feature is gait disturbance which reduces quality of life for the patients. The available clinical scales are not only subjective but also limited to the clinical setting. An objective measure such as mobile gait analysis would allow the continuous monitoring of the disease progression, and variability as well as allow the effective analysis of intervention effect in the environment where it matters the most for quality of life, the home environment. HSP is a heterogenous disease with varying age of onset, severity and progression, as well as a variety of ground contact techniques such as toe walking and foot drag. In this project we develop algorithms which can accurately estimate gait parameters from such patients using a mobile gait analysis system.

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